Glial cell line-derived neurotrophic factor (GDNF) is highly expressed in all types of gliomas, regardless of grade or form (Ayanlaja et al., 2018), and this expression pattern contributes to the recruitment and activation of caner-associated fibroblasts, leading to an inflammatory response (Tape et al., 2016). The gene discussed is GDNF; the disease is central nervous system cancer.