BECN1 and non-small cell lung carcinoma: Simultaneously, the autophagic response exerted by flubendazole in the NSCLC in vivo model was also confirmed; the levels of Beclin-1 and LC3-I/II proteins increased, whereas those of mTOR and P62 were decreased following exposure to flubendazole (Figure 6E and Supplementary Figure 1D).