STAT3 and carcinoma: Moreover, STAT3 is constitutively active in various carcinomas, including colon, prostate, breast, and lung carcinomas (Mora et al., 2002; Banerjee and Resat, 2016; Huynh et al., 2019; Lin et al., 2019; Wei et al., 2019; Yang et al., 2020; Zhao et al., 2020).