Furthermore, we performed western blot analysis of protein expression related to energy metabolism in the xenograft tumors of Hela, and found that OIP5-AS1 knocked down by Si-AS1 could decreased the expression of LDHA, GULT1, and HIF-1α protein in the xenograft tumors of Hela (Figure 2F), suggesting that OIP5-AS1 might be a oncogene which was related to energy metabolism in cervical cancer. This evidence concerns the gene HIF1A and cervical carcinoma.