OIP5 and cervical carcinoma: Compared with cervical cancer cells transfection to Si-NC, intracellular α-KG levels of cervical cancer cells knocking down OIP5-AS1 by transfection to Si-AS1 was significantly increase (Figure 4A), but levels of intracellular 2-HG was significantly decrease (Figure 4B), and the levels of ROS (Figure 4C) and ratio of NADP+/NADPH (Figure 4D) were all significantly increase.