Type 1 diabetes mellitus (T1DM) is a chronic metabolic disease that is characterized by the production of insufficient or no insulin as a result of the destruction of β-cells (Y. J. Lin et al., 2019), which can result in hyperglycemia, hypoglycemic unawareness, and ketoacidosis (Omami et al., 2017). The gene discussed is INS; the disease is type 1 diabetes mellitus.