To assess the impact of RhoA and RhoC expression on long-term ISG expression, SUM 149 and MDA 231 wild-type, crRhoA and crRhoC cells were treated with IFN-α at 100 IU/ml for 72 hours, then RNA was harvested and a relevant array of cancer related genes was assessed by the nanoString Pan-Cancer Immune Panel. This evidence concerns the gene IFNA1 and cancer.