BCL2 and neoplasm: Apoptosis related examinations including the increased expression of TUNEL, BAX protein, cleaved caspase-3 protein and the decrease of Bcl-2 protein, all proved the changes in apoptosis related proteins in tumor tissue (30).The related indicators—HSPs and apoptosis -related proteins—were assessed to confirm the ability of the model to detect protein level changes in a short time after incomplete ablation.