This study revealed three clusters, each with similar molecular make up, including 40% of cases with a “SCLC- like” with TP53 and RB1 alterations, and 56% of cases described as “NSCLC- like” with STK11, KRAS, KEAP1-NFE2L2 alterations which are more typical of adenocarcinoma or squamous cell carcinoma. The gene discussed is TP53; the disease is small cell lung carcinoma.