It was also proved that GAS6-AS1/miR-585/EIF5A2 pathway played an important role in the progression of hepatocellular carcinoma (14), Zhang et al. indicated that indicate that GAS6-AS1 significantly driving the aggressive phenotype in gastric cancer through activating its cognate sense gene GAS6 (15). This evidence concerns the gene GAS6 and hepatocellular carcinoma.