Nowak-Göttl et al. used AT III without heparin in 21 preterm infants and 18 children with sepsis-induced DIC and found that there was normalization of plasma level of AT III, platelet count, fibrinogen, PT, APTT, and thrombin time within 24-48 hours without any observed side effects or mortality [26]. The gene discussed is SERPINC1; the disease is Sepsis.