F2 and systemic inflammatory response syndrome: DIC, disseminated intravascular coagulation; FDP, fibrin degradation products; FEU, fibrinogen equivalent unit; INR, international normalized ratio; ISTH, International Society on Thrombosis and Hemostasis; JAAM, Japanese Association for Acute Medicine; JMHLW, Japanese Ministry of Health, Labor and Welfare; PT, prothrombin time; SIRS, systemic inflammatory response syndrome; TCH, Texas Children’s Hospital.