Recent cardiovascular outcome trials (CVOTs) with SGLT2 inhibitors have shown to boost cardiovascular and renal outcomes in patients both with T2DM and without T2DM, with the American Diabetes Association (ADA) and The European Association for the Study of Diabetes (EASD) recommending them as a core component of T2DM therapy [11]. Here, SLC5A2 is linked to diabetes mellitus.