ARG1 and Chronic colitis: Several studies have expounded on its anti-inflammatory and antioxidant properties to prove its linkage to the improvement of dextran sodium sulfate (DSS)-induced colitis, IL-10−/− chronic colitis in mice, and resveratrol-induced immunosuppressive CD11b+ Gr-1+ cells that express ARG-1, which correlated with reversal of chronic colitis severity [25].