Ryan et al. compared preoperative albumin to ASA score and showed that both were significant predictors of death, superficial infections, pneumonia, renal insufficiency, reintubation, transfusion, readmissions, and reoperations; however, hypoalbuminemia was more robust in predicting deep wound infections in total hip arthroplasty and superficial wound infections in total knee arthroplasty [15]. The gene discussed is ALB; the disease is Hypoalbuminemia.