Notably, miR-140-3p belongs to the miR-140 cluster and has been shown to play an important role in the occurrence and development of a variety of tumours; miR-140-3p inhibits the proliferation of human cervical cancer cells by targeting RRM2 to induce cell cycle arrest and early apoptosis (Ma, Zhang & Sun, 2020). This evidence concerns the gene RRM2 and neoplasm.