Between 4 h and 120 h after administration, uptake profiles of the antibodies in various organs were qualitatively similar to those in the tumor-bearing animals, with high accumulation in the liver and low accumulation in the blood and spleen for anti-CSPG4 IgE, and higher persistence in the circulation and increasing accumulation in the spleen for anti-CSPG-IgG (Fig. S4). This evidence concerns the gene IGHE and neoplasm.