Finally, Haba et al. usefully distinguished between an earlier phase and a later phase for their t1/2 calculations, with an apparent half-life of around 1.5–2 h in the first six hours and 5–8 h over the following days.28 In our initial experiment in tumor-bearing mice, primarily aimed at comparing antibody uptake in the tumors, we initially sampled 4 h after administration and found an apparent blood half-life of 7.3 h for the anti-CSPG4 IgE, in line with the aforementioned studies. Here, IGHE is linked to neoplasm.