It is reported that PD1 is widely expressed in ccRCC, whereas the other inhibitory receptor such as TIM-3, CTLA4, and 4-1BB are only expressed in few PD1+ clusters, and CD38 is also widely expressed and may work as a latent T cell exhaustion marker [30]. Here, TNFRSF9 is linked to nonpapillary renal cell carcinoma.