There is also growing evidence of high eIF5B expression levels in various malignancies like GBM, lung adenocarcinoma (LUAD) and hepatocellular carcinoma (HCC), signifying the importance of eIF5B as the stress-related tumorigenic eIF (Wang et al., 2016; Ross et al., 2019; Suresh et al., 2020). This evidence concerns the gene EIF5B and glioblastoma.