The 11 selected thyroid-specific RNA transcripts (TPO, TG, GFRA2, IYD, PDE8B, WDR86, C16orf89, DGKI, DIO2, TSHR, and PAX8) were amplified from healthy volunteers (Supplementary Figure 2A) and thyroid patients (Supplementary Figure 2B). The gene discussed is IYD; the disease is thyroid gland disorder.