Abnormal expression of the miR-199 cluster, for example, has been confirmed to increase the sensitivity of ovarian cancer cells to DDP through silencing the expression of protein tyrosine phosphatase non-receptor type 3 (PTPN3), integrin subunit beta 8 (ITGB8) and discoidin domain receptor 1 (DDR1) (Li S. et al., 2016; Deng et al., 2017; Cui et al., 2018). Here, ITGB8 is linked to ovarian cancer.