According to a recent report, miR-493-5p is significantly upregulated in BRCA2-mutated ovarian cancer cells and it participates in the PARPi resistance process by regulating ribonuclease H2 subunit A (RNASEH2A), flap structure-specific endonuclease 1 (FEN1), and structure specific recognition protein 1 (SSRP1). The gene discussed is RNASEH2A; the disease is ovarian carcinoma.