Extra spindle pole bodies-like 1 expression in various tumors and matched normal tissues was assessed using the GEPIA online tool (Figure 1A); we observed that ESPL1 was abnormally highly expressed in a variety of malignant tumor tissues, including GBM, while the ESPL1 expression level of esophageal carcinoma (ESCA) was lower than that in normal tissues. The gene discussed is ESPL1; the disease is neoplasm.