Extra spindle pole bodies-like 1 expression in various tumors and matched normal tissues was assessed using the GEPIA online tool (Figure 1A); we observed that ESPL1 was abnormally highly expressed in a variety of malignant tumor tissues, including GBM, while the ESPL1 expression level of esophageal carcinoma (ESCA) was lower than that in normal tissues. This evidence concerns the gene ESPL1 and cancer.