LRFN4 and gastric adenocarcinoma: To verify the difference in LRFN4 and CTHRC1 expression in the TCGA database, qRT-PCR was used to evaluate the mRNA expression level of LRFN4 and CTHRC1, which showed that their expressions in STAD were both significantly higher than that in adjacent normal tissues (p < 0.05, Figures 8C,D).