CRP and renal cell carcinoma: In a prospective study of 111 patients undergoing either partial or radical nephrectomy for RCC in whom CRP was measured preoperatively, tumor infiltration of CD8 T-cells, M2 macrophages, and regulatory T cells on immunohistochemical staining were associated with elevated CRP, which, in turn, correlated with worse cancer specific survival (CSS) (Table 1).