In a 1978 study of lactating women, de Waal et al. found that vB6 (300–1,200 mg) did not reduce chlorpromazine-induced hyperprolactinemia, but perhaps this negative conclusion should be re-considered given that the women were actively producing milk, a physiological process that requires elevated prolactin (22). The gene discussed is PRL; the disease is hyperprolactinemia.