Inherently low levels of immune infiltration including macrophages (CD45 + CD11b + F4/80+) were presented in B16-F10 melanoma, and myeloid cells (CD11b+) from 4T1 tumors were found to exert suppress proliferation of T cells more than myeloid cells from B16-F10 (De Henau et al., 2016; Aznar et al., 2019). Here, ITGAM is linked to melanoma.