PRMT5 and cancer: Decreases the phosphorylated Akt, PRMT5 and NF-κB via upregulation of p53 and HO-1; promotes cancer cell apoptosis (Bcl-2↓, Bcl-xl↓, cyclin D1↓, cyclin E1↓); inhibits invasion (MMP-9↓; MMP-2↓)