TOMM40 and Alzheimer disease: A longitudinal blood transcriptomic study identified a consistent downregulation of TOMM40 (translocase of outer mitochondrial membrane 40 homolog) in AD patients and upregulation of several leukocyte-specific genes among those with rapidly vs. slowly advancing disease, including KIR2DL5A (killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A), SLC2A8 (solute carrier family 2, facilitated glucose transporter, member 2), and PLOD1 (procollagen-lysine 2 o-oxoglutarate 5-dioxygenase 1; Chong et al., 2013).