Other studies in patients with intractable temporal lobe epilepsy and rodents with induced seizures have demonstrated the upregulation of CCL2 in the hippocampus and other brain areas (Wu et al., 2008; Banks and Erickson, 2010; Varvel et al., 2016; Orsini et al., 2021). The gene discussed is CCL2; the disease is temporal lobe epilepsy.