GPR83 and Anxiety: We find that local GPR83 KD in the BLA resulted in a decrease in the amount of time spent (unpaired t-test, t = 5.223, df = 23, ∗∗∗p < 0.001) and frequency to enter (unpaired t-test, t = 3.119, df = 22, ∗∗p < 0.01) the open arm of the EPM indicating an increase in anxiety-related behaviors (Figures 5B,C).