Kaempferol activates the inositol-requiring enzyme 1 (IRE1)1/Jun n-terminal kinase (JNK)/C/EBP homologous protein 10 (CHOP) pathway from the cytosol to the nucleus and promotes autophagic cell death by inhibiting the histone deacetylase (HDAC)/G9a axis in gastric cancer (62). This evidence concerns the gene MAPK8 and gastric cancer.