To explore the prognostic value of the expression levels of the 21 m6A methylation regulators in A-HCC, we performed univariate Cox regression analysis based on the expression levels of related factors in TCGA dataset and found seven related genes to be significantly related to OS (p < 0.05), namely YTHDF2, KIAA1429, YTHDF1, RBM15B, LRPPRC, RBM15, and YTHDF3 (Supplementary Table 5). The gene discussed is YTHDF3; the disease is hepatocellular carcinoma.