Other proteins closely related to A-HCC include patatin-like phospholipase domain-containing protein 3 (PNPLA3), hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13), serpin family A member 1 (SERPINA1), and transmembrane 6 superfamily member 2 (TM6SF2) 37-40. Here, PNPLA3 is linked to hepatocellular carcinoma.