Furthermore, WB (Figure 9F) and immunohistochemical assays (Figure 9G) of the tumor tissue indicated that TQ treatment also upregulated the level of cleaved PARP, E-cad, LC3B and p62 proteins, in the meantime reduced the expression of N-cad, MMP2 and PD-L1 proteins. This evidence concerns the gene SQSTM1 and neoplasm.