Molecular mechanism investigations have shown that NEAT1 promotes HCC cell proliferation, migration, and invasion by upregulating the expression of calponin 2 (CNN2), transforming growth factor-β1 (TGF-β1), and STAT3 by targeting miR-296-5p, miR-139-5p, and miR-485, respectively 60-62. This evidence concerns the gene CNN2 and hepatocellular carcinoma.