CDH2 and metastatic malignant neoplasm in the lymph nodes: However, the percentages of T3 clinical stage (low:high = 20.0%:33.3%), lymph node metastasis (low:high = 16.7%:36.7%), and distant metastasis (low:high = 6.7%:16.7%) were higher in the group with high N-cadherin levels.