Indeed, it was reported in a cohort of 54 COVID-19 patients who died from the infection, it was found those patients had higher levels of D-dimer, troponin, and interleukin-6 (IL-6).18 Furthermore, Wang et al19 reported that, among 199 COVID-19 patients, elevated levels of D-dimer, fibrinogen degradation products, prolonged prothrombin time, and thrombin time were found to be higher among patients with severe disease manifestations. Here, F2 is linked to COVID-19.