The prognostic importance of NPC1L1 with that of other markers, such as vascular endothelial growth factor A (VEGF-A), metastasis-associated in colon cancer 1 (MACC1), and transforming growth factor-beta 1 (TGF-β1) with respect to CRC was also compared (Table 4). This evidence concerns the gene NPC1L1 and colorectal carcinoma.