Next, to evaluate whether OGT regulates the expression of EZH2 to influence live cancer progression, OGT was overexpressed or silenced EZH2 in HCC‐LM3 and Huh‐7 cells as follows, oe‐NC + si‐NC, oe‐OGT + si‐NC, and oe‐OGT + si‐EZH2. The gene discussed is EZH2; the disease is cancer.