KDM6A and hepatocellular carcinoma: Moreover, we probed for KDM6A protein expression in a tissue microarray comprising 39 normal liver tissues and 459 HCCs (online supplemental table 2) and found that nearly all normal liver tissues expressed a detectable but low nuclear expression of KDM6A, whereas KDM6A was absent in approximately 30% of HCCs (figure 1B) and a small proportion of HCC cases showed elevated KDM6A expression.