Finally, to translate our findings into the human setting, we first correlated mRNA expression levels of KDM6A and DEPTOR in a cohort of 76 human HCCs and corresponding normal liver samples and found that only in HCC samples KDM6A and DEPTOR transcripts showed a strong positive correlation (R=0.4236, p=0.0022 vs R=0.04983, p=0.7311) (figure 7A, B). Here, DEPTOR is linked to hepatocellular carcinoma.