According to the above results, the inhibitory effect of 20% of the IC50 for both drugs is less limiting; 40% of the IC50 for BGB-3111 combined with 40% of the IC50 for BTZ could almost inhibit half of the cell proliferation, and we would like to use a low concentration to achieve a good inhibitory effect on the tumor cell growth. The gene discussed is CASC3; the disease is neoplasm.