MKI67 and neoplasm: While the difference in Ki67 expression between the ASO 3 and NTC ASO treated mice was too small to be statistically significant (Fig. 5E, F, p = 0.3577, unpaired t-test), further investigation of the mitotic index showed a significant reduction in the number of mitotic cells in the ASO 3 treated tumor samples (Fig. 5E, G, p = 0.0278, unpaired t-test).