BAP1 and metastatic neoplasm: SAMMSON expression was further verified by RT-qPCR in various UM cell lines originating from primary tumors (92.1 and MEL270) and metastatic tumors (OMM2.3 and OMM1) (Fig. 1C), as well as in UM PDX-derived cell lines (MP38 (BAP1 negative, monosomy 3), MP46 (BAP1 negative, monosomy 3), MEL077, MP65 (BAP1 negative, monosomy 3), and MM28) (Fig. 1D).