Seven types of recurrent ROS1 fusions were identified in our data, including the well described CD74-ROS1, EZR-ROS1, SDC4-ROS1, SLC34A2-ROS1, TPM3-ROS1, and MYH9-ROS122,23, as well as a novel recurrent fusion, SLC12A2-ROS1, which was identified as a novel fusion in inflammatory myofibroblastic tumors (Fig. 2b). The gene discussed is SDC4; the disease is inflammatory myofibroblastic tumor.