IFNA1 and hepatocellular carcinoma: In order to obtain a genome-wide view of the network of coding and non-coding RNA genes in IFN treated hepatoma cells and to identify possible novel effectors of IFN antiviral activity we applied to our set of RNA sequencing data a systems biology approach modeled on independent phenotypical pattern of the two well-known IFN sensitive genes19 individually measured in the populations of IFN-treated and untreated hepatoma cell lines.