In the patients with endometrial cancer, some hub genes, including PBK, BIRC5, AURKA, GTSE1, KNSTRN, and PSMB10, were detected to be associated with AKT1. Hence, the higher expression of AKT1 was observed to be significantly associated with developing the endometrial cancer69. The gene discussed is PSMB10; the disease is endometrial cancer.