We compared the gene expression analysis of Weiget et al. by means of the calculated TRIM24 metaplastic score and found that this cohort of human MpBC tumors has a significantly higher TRIM24 metaplastic score than TRIM24-driven carcinomas, as did TRIM24-driven metaplastic carcinosarcomas (Supplementary Fig. 3d), predicting that TRIM24 is activated in human metaplastic tumors. Here, TRIM24 is linked to carcinoma.