IFNA1 and infection: After infection with SeV or influenza A H1N1 virus for different time periods, ELISA assays of the supernatants revealed that both early phase (4 h) and late phase (24 h) IFN-α production was significantly impaired in BMDMs from Uba3ΔMye mice, as compared to those from littermate control mice (Fig 1B and 1C).