However, when multivariable correction factors were reduced for analysis (adjusted for BUN (or BUN residual), age, sex, eGFR, UPCR, DM, CCI, log CRP, albumin, TSAT, and ferritin), there was no significant association of BUN, BUN residual, and eGFR with anemia development. The gene discussed is ALB; the disease is anemia (phenotype).