In the model fully adjusted for age, sex, smoking, SBP, DM, HTN, CCI, eGFR, log UPCR, WBC, platelet, platelet, log CRP, albumin, total cholesterol, log ferritin, log hepcidin, iron, TSAT, iron replacement therapy, ESA, ACEi or ARB, statin, and diuretics, the hemoglobin level was significantly associated with BUN (β -0.03; 95% CI -0.04, -0.03; P <0.001). The gene discussed is HAMP; the disease is hypertensive disorder.