IFNG and malaria: The purpose of this study was therefore to determine the effect of polymorphisms in peptide sequences on the induction of IFN-γ responses by identifying immunodominant peptides from the 3D7 parasite strain AMA1 and comparing IFN-γ responses of these with corresponding responses from allelic peptides from other parasite strains in subjects naturally exposed to malaria parasites in an endemic area.