IFNG and malaria: This study therefore investigated the effect of allelic polymorphisms in MHC-restricted peptides from AMA1 on ex-vivo malaria parasite-specific IFN-γ responses in subjects with a history of natural exposure to malaria infections using allelic AMA1 peptide sequences from the 3D7, 7G8, FVO, FC27 and tm284 P. falciparum strains.