GXYLT2 and neoplasm: Previous reports showed that GXYLT2 could promote glycosyltransferase expression in human myeloid leukemia cells via Notch pathway activation, and it could also promote cell proliferation and migration by altering the Notch pathway in a variety of tumor cells [7], such as MDA-MB-231, BGC-823 and SGC-7901 cells [8].