High expression of CCT3 was found in some cancers, such as hepatocellular carcinoma, multiple myeloma, colorectal cancer, liver cancer and gastric cancer [12,19–22], and increased expression of CCT3 was not only indicated a poor prognosis in patients with hepatocellular carcinoma but also correlated with lymph-node metastasis of gastric cancer [23,24]. The gene discussed is CCT3; the disease is liver cancer.