For CRP, per-unit increase in genetically-predicted concentrations of log-transformed CRP was associated with lower risk for depressive symptoms (1-sample MR: OR=0·89; 95% CI, 0·79–1·00; 2-sample MR: OR=0·88; 95% CI, 0·80–0·98), and lower risk for anxiety symptoms (1-sample MR: OR=0·88; 95% CI, 0·79–0·97; 2-sample MR: OR=0·87; 95% CI, 0·80–0·95). The gene discussed is CRP; the disease is Anxiety.