The presence of significant high serum copper levels in nonalcoholic fatty liver disease (NAFLD) in cirrhotic patients increased cell growth, migration, and invasion of liver cancer cells through the modulation of the MYC/CTR1 axis (MYC proto-oncogene, bHLH transcription factor/copper transport protein) (Porcu et al., 2018). Here, MYC is linked to metabolic dysfunction-associated steatotic liver disease.