The protein levels of MMP‐2, MMP‐3, MMP‐7, MMP‐8, MMP‐9, MMP‐12, MMP‐13, TIMP‐1, TIMP‐2, TIMP‐3, TIMP‐4, periostin and tenascin C were examined in tissue homogenates from patients with CRS. The gene discussed is TIMP3; the disease is congenital rubella syndrome.